ALL PUBLICATIONS

 

2017

Mendelsohn AIDasen JSJessell TM. (2017) Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles. Neuron, 93, 792-805  

2016

Reardon T.R., Murray A.J., Turi G.F., Wirblich C., Croce, C., Schnell T., Jessell, T.M. and Losonczy, A. (2016) Rabies virus CVS-N2cΔG strain enhances retrograde synaptic transfer and neuronal viability. Neuron, 89, 711-724.

Poliak, S., Norovich, A.L., Yamagata, M., Sanes, J.R., and Jessell T.M. (2016) Muscle-type identity of proprioceptors specified by spatially-restricted signals from limb mesenchyme. Cell, 164, 512-525.

Bikoff, J.B., Gabitto, M.I., Rivard, A.F., Drobac, E., Machado, T.A., Miri, A., Brenner-Morton S., Famojure, E., Diaz, C., Alvarez, F.J., Mentis, G.Z., and Jessell, T.M., (2016) Spinal inhibitory interneuron diversity delineates variant motor microcircuits. Cell, 165, 207-219.

Gabitto, M.I., Pakman, A., Bikoff, J.B., Abbott, L.F., Jessell, T.M., and Paninski, L. (2016) Bayesian sparse regression analysis documents the diversity of spinal inhibitory interneurons. Cell, 165, 220-233.

Pnevmatikakis, E.A., Soudry, D., Gao, Y., Machado, T., Merel, J., Pfau, D., Reardon, T., Mu, Y., Lacefield, C., Yang.,W., Ahrens, M., Bruno, R., Jessell, T., Peterka, D.S., Yuste, R., and Paninski, L. (2016) Simultaneous denoising, deconvolution, and demixing of calcium imaging data. Neuron, 89, 285-299.

Jager P, Ye Z, Yu X, Zagoraiou L, Prekop HT, Partanen J, Jessell TM, Wisden W, Brickley SG, Delogu A. Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus. Nature Communications 7, Article number: 13579

2015

deNooij, J.C., Simon, C.M., Simon, A., Doobar, S., Steel, K.P., Banks, R.W., Mentis, G.Z., Bewick, G.S., and Jessell, T.M. (2015). The PDZ-domain protein whirlin facilitates mechano-sensory signaling in mammalian proprioceptors. Journal of Neuroscience, 35, 3073-3084.

A. I. Mendelsohn, C. M. Simon, L.F. Abbott, G. Z. Mentis and T. M. Jessell (2015) Activity regulates the incidence of heteronymous sensory-motor connections Neuron 87, 111-123.

Machado, T.A., Pnevmatikakis, E., Paninski, L., Jessell, T.M., and Miri, A. (2015) Primacy of flexor locomotor pattern revealed by ancestral reversion of motor neuron identity. Cell, 162, 338-350.

Woo, S.H, Lukacs, V., de Nooij J.C., Zaytseva, D., Criddle, C.R., Francisco, A., Jessell T.M., Wilkinson, K.A., and Patapoutian, A. (2015) Piezo2 is the principal mechanotransduction channel for proprioception. Nature Neuroscience, 18, 1756-1762

2014

Ashrafi, S., Betley, J.N., Comer, J.D., Brenner-Morton, S., Bar, V., Shimoda, Y., Watanabe, K., Peles, E., Jessell, T.M., and Kaltschmidt, J.A. (2014). Neuronal Ig/Caspr recognition promotes the formation of axo-axonic synapses in mouse spinal cord. Neuron 81, 120-129.

Zampieri, N., Jessell, T.M. and Murray, A.J. (2014) Mapping sensory circuits by anterograde trans-ynaptic transfer of recombinant rabies virus. Neuron, 81, 766-778. 

Azim, E., Jiang, J., Alstermark, B., and Jessell, T.M. (2014). Skilled reaching relies on a V2a propriospinal internal copy circuit. Nature, 508, 357-363 (2014)

Fink, A.J., Croce K. R., Huang, Z.J., Abbott, L.F., Jessell, T.M. and Azim, E. (2014) Presynaptic inhibition of spinal sensory feedback ensures smooth movement. Nature, 509, 43-48 

Akay, T., Arber, S., Tourtellotte, W.G., and Jessell, T.M. Degradation of mouse locomotor pattern in the absence of proprioceptive sensory feedback. PNAS. Nov 11. pii: 201419045. [Epub ahead of print]

Azim, E., Fink, AJ, and Jessell TM (2014) Internal and external feedback circuits for skilled forelimb movement. Cold Spring Harbor Symp. Quant. Biol. 79, 81-92.

2013

de Nooij, J.C., Doobar, S., and Jessell, T.M. (2013). Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets. Neuron. 77, 1055-1068.

Bui, T.V., Akay, T., Loubani, O., Hnasko, T.S., Jessell, T.M., and Brownstone, R.M. (2013). Circuits for grasping: spinal dI3 inerneurons mediate cutaneous control of motor behavior. Neuron.78, 191-204.

Dougherty, K.J., Zagoraiou, L., Satoh, D., Rozani, I., Doobar, S., Arber, S., Jessell, T.M., and Kiehn O. (2013). Locomotor rhythm generation linked to the output of spinal Shox2 excitatory interneurons. Neuron, 80, 920-933.

Fukuhara, K., Imai, F., Ladle, D.R., Katayama, K., Leslie, J.R., Arber, S., Jessell, T.M., and Yoshida, Y. (2013). Specificity of monosynaptic sensory-motor connections imposed by repellent sema3E-plexinD1 signaling. Cell Reports 5, 748-758.

Miri, A., Azim, E., Jessell, T.M. (2013). Edging towards Entelechy in Motor Control. Neuron, 80, 827-834.

2012

Kuwajima, T., Yoshida, Y., Takegahara, N., Kumanogoh, A., Petros, T.J., Jessell, T.M., Sakurai, T., and Mason, C.(2012) Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron. 74, 676-690.

Delogu, A., Sellers, K., Zagoraiou, L., Bocianowska-Zbrog, ,A.. Mandal, S. ,Guimera, J., Rubenstein, J.L.R., Sugden, D., Jessell, T., Lumsden, A. (2012). Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 75, 648-662.

2011

Alaynick WA, Jessell TM, and Pfaff SL. (2011) SnapShot: spinal cord development. Cell. 146, 178.

Demireva, E., Shapiro, L. S. Jessell, T.M. and Zampieri, N. (2011) Motor neuron position and topographic order imposed by β- and γ-catenin activities. Cell. 147, 641-652.

Sürmeli, G., Akay, T., Ippolito, G., Tucker P.W. and Jessell, T.M. (2011) Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional template. Cell. 147, 653-665.

Jessell, T.M., Sürmeli, G., and Kelly, J.S. (2011) Motor neurons and the sense of place. Neuron. 72, 419-424.

2010

Ciatto, C., Bahna, F., Zampieri, N., VanSteenhouse, H.C., Ranscht, B., Katsamba, P., Ahlsen, G., Posy, S., Vendome, J., Jessell, T.M., Honig, B., and Shapiro, L. (2010). T-cadherin structures reveal a novel cadherin adhesive binding mechanism. Nature Structural Biology, 17, 339-347.

Peljto, M., Dasen. J.S., Mazzoni, E.O., Jessell, T.M., and Wichterle, H. (2010). Functional diversity of ESC-derived motor neuron subtypes reveled through intraspinal transplantation. Cell Stem Cell 7, 355-366.

Hantman, A.W. and Jessell, T.M. (2010). Clarke's column neurons as the focus of a corollary discharge circuit. Nature Neuroscience. 13, 1233-1239. Nature Neuroscience. 13, 1233-1239.

Lek, M., Dias, J.M., Marklund, U., Uhde, C.W., Kurdija, S., Lei, Q., Sussel, L., Rubenstein, J. L., Matise, M.P., Arnold, H-H, Jessell, T.M., and Ericson, J. (2010). A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development. 137, 4051-4060.

2009

Agalliu, D., Takada, S., Agalliu, I., McMahon, A.P., and Jessell, T.M. (2009). Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron, 61, 708-720.

Katsamba, P., Carroll, K., Ahlsen, G., Bahna, F., Vendome, J., Posy, S., Rajebhosale, M., Price, S., Jessell, T.M., Ben-Shaul, A., Shapiro, L., and Honig, B. (2009). Linking molecular affinity and cellular specificity in cadherin-mediated adhesion. Proc. Natl. Acad. Sci. USA, 106, 11594-11599.

Dasen, J.S. and Jessell, T.M. (2009). Hox networks and the origins of motor neuron diversity. Current Topics in Developmental Biology, 88, 1-32.

Pecho-Vrieseling, E., Sigrist, M., Yoshida, Y., Jessell, T.M. and Arber, S. (2009). Specificity of sensory-motor connections encoded by sema3e-plexinD1 recognition. Nature, 459, 842-846.
 

Friese, A., Kaltschmidt, J.A., Ladle, D.R., Sigrist, M., Jessell, T.M. and Arber S. (2009). Gamma and alpha motor neurons distinguished by expression of transcription factor Err3. Proc. Natl. Acad. Sci. USA 106, 13588-13593.

Zagoraiou, L., Akay, T., Martin, J.F., Brownstone, R.M., Jessell, T.M., and Miles G.B. (2009). A cluster of cholinergic pre-motor interneurons modulates mouse locomotor activity. Neuron, 64, 645-662.

Betley, J.N., Wright, C., Kawaguchi, Y., Erdelyi, F., Szabo, G., Jessell, T.M., and Kaltschmidt, J.A. (2009) Stringent specificity in the construction of a GABAergic pre-synaptic inhibitory circuit. Cell, 139, 161-174

Grillner, S., and Jessell, T.M. (2009) Measured motion: searching for simplicity in spinal locomotor networks. Current Opinion in Neurobiology. 19, 572-586.

2008

DeMarco Garcia, N.V. and Jessell, T.M. (2008). Early motor neuron pool identity and muscle nerve trajectory defined by post-mitotic restrictions in Nkx6.1 activity. Neuron, 57, 217-231.

Dasen, J., De Camilli, A., Wang, B., Tucker, P.W. and Jessell, T.M. (2008). Hox repertories for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell, 134, 304-316.

Crone, S.A., Quinlan, K.A., Zagoraiou, L., Droho, S., Restrepo, E., Lundfald, L., Endo, T., Setlak, J., Jessell, T.M., Kiehn, O., and Sharma, K. (2008). Genetic ablation of V2a ipsilateral interneurons disrupts left-right locomotor coordination in mammalian spinal cord. Neuron, 60, 70-83.

Lauria, V., Krawchuk, D., Jessell, T.M., Laufer, E., and Kania, A. (2008). Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron, 60, 1039-1053.

2007

Nagai, M., Re, D.B., Nagata, T., Chalazonitis, A., Jessell, T.M., Wichterle, H., and Przedborski, S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nature Neuroscience 10, 615-622.

Chauvet, S., Cohen, S., Yoshida, Y., Fekrane, L., Gayet, O., Segu, L., Buhot, Jessell, T.M., Henderson, C.E., and Mann, F. Gating of Sema3E/PlexinD1 signaling by Neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron I56, 807-822

2006

Yoshida Y., Han B., Mendelsohn M., Jessell T.M. Plexin A1 Signaling Directs the Segregation of Proprioceptive Sensory Axons in the Developing Spinal Cord. Neuron 2006 Dec 7;52(5):775-88.

Kramer, I., Sigrist, M., de Nooij, J.C., Taniuchi, I., Jessell, T.M., and Arber, S. Runx transcription factor signaling contributes to the emergence of specific sensory neuron subpopulations. Neuron 49, 379-393.

Nordstrom, U. Maier, E., Jessell, T.M., and Edlund, T. (2006). An early role for Wnt signaling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity. Plos Biology, 4, e252-e266.

Patel, S.D., Ciatto, C., Chen, C.P., Bahana, F., Rajebhosale, M., Arkus, N., Schieren, I., Jessell, T.M., Honig, B., Price, S.R., and Shapiro, L. Type II cadherin ectodomain structures: Implications for classical cadherin specificity. Cell 124, 1255-1268.

Mukouyama, Y.-S., Deneen, B., Lukaszewicz, A., Novitch, B.G., Wichterle, H., Jessell, T.M., and Anderson, D.J. Olig2+ neuroepithelial motor neuron progenitors are not multipotent stem cells in vivo. Natl. Acad. Sci. USA, 1551-1556.

Chen, A.I., de Nooij, J.C. and Jessell, T.M. (2006). Graded activity of transcription factor Runx3 specifies the laminar termination pattern of sensory axons in the developing spinal cord. Neuron 49, 395-408.

Chen, C.-L., Broom, D.C., Liu, Y., de Nooij, J.C., Li, Z., Cen, C., Samad, O.A., Jessell, T.M., Woolf, C.J., and Ma, Q. (2006). Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron 49, 365-377.

2005

Gu, C., Yoshida, Y., Livet, J., Reimert, D.V., Mann, D., Merte, J., Henderson , C.E., Jessell, T.M., Kolodkin, A.L., and Ginty, D.D. (2005). Semaphorin 3E and its receptor plexin-D1 control vascular patterning independently of neuropilins. Science 307 265-268

Wilson, J.M., Hartley, R., Maxwell, D.J., Todd, A.J., Lieberam, I., Kaltschmidt, J.A., Yoshida, Y., Jessell, T.M., and Brownstone, R.M. (2005). Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein. J Neurosci, 2005 Jun 15;25(24):5710-9

Huber, A.B., Kania, A., Tran, T.S., Gu, C., de Marco, N., Lieberam, I., Johnson, D., Jessell, T.M., Ginty, D.D., and Kolodkin, A.L. Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron, 48, 949-964.

Dasen, J.S., Tice, B.C., Brenner-Morton, S. and Jessell, T.M. A Hox regulatory network establishing motor neuron pool identity and target muscle connectivity. Cell 123, 477-491.

2004

Thaler, J.P., Lettieri, K., Andrews, S., Cox, C., Jessell, T.M., and Pfaff, S.L. (2004). Post-mitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron 41, 337-350.

Lanuza, G.M., Gosgnach, S., Pierani, A., Jessell, T.M., and Goulding, M. (2004). Genetic identification of spinal interneurons that coordinate left-right locomotor activity. Neuron 42, 375-386.

Marklund, M., Sjodal, M., Beehler, B.C., Jessell, T.M., Edlund, T., and Gunhaga, L. (2004). Retinoic acid signaling specifies intermediate character in the developing telencephalon. Development, 131, 4323-4333.  

Miles, G.B., Yohn, D.C., Wichterle, H., Jessell, T.M., Rafuse, V.F., and Brownstone, R.M. (2004). Functional properties of motoneurons derived from mouse embryonic stem cells. J. Neurosci. 24, 7848-7858.

2003

William, C.M., Tanabe, Y. and Jessell, T.M. (2003). Regulation of motor neuron subtype identity by repressor activity of Mnx homeodomain proteins. Development, 130, 1523-1536.

Gunhaga L, Marklund M, Sjodal M, Hsieh JC, Jessell TM, Edlund T. (2003). Specification of dorsal telencephalic character by sequential Wnt and FGF signaling. Nat. Neurosci. 6, 701-707. 

Kania, A. and Jessell, T.M. (2003). Post-mitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron, 38, 581-596.

Patel, T.D., Kramer, I., Kucera, J., Niederkofler, V., Jessell, T.M., Arber, S., and Snider, W.D. (2003). Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents. Neuron, 38 403-416.

Brivanlou, A.H., Gage, F.H., Jaenisch, R., Jessell, T., Melton, D., and Rossant, J. (2003). Setting standards for human embryonic stem cells. Science 300, 913-916.

Novitch, B.G., Wichterle, H., Jessell, T.M., and Sockanathan, S. (2003). A requirement for retinoic acid mediated transcriptional activation in ventral neural patterning and motor neuron specification. Neuron, 2003 Sep 25;40

Sockanathan, S., Perlmann, T. and Jessell, T.M. (2003). Post-mitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron. 2003 Sep 25;40(1):97-111.

Dasen, J.S., Liu, J-P., and Jessell, T.M. (2003). Motor neuron columnar fate imposed by sequential phases of Hox-c activity. Nature. 2003 Oct 30;425(6961):926-33.

2002

Price, S.R., De Marco Garcia, N.V. Ranscht, B. and Jessell, T.M. (2002). Regulation of motor neuron pool sorting by differential expression of type II cadherins. Cell, 109, 215-216.

Muller, T., Brohmann, H., Pierani, A., Heppenstall, P.A., Lewin, G.R., Jessell, T.M., and Birchmeier, C. (2002) The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord. Neuron, 34, 551-562.

Nordstrom, U., Jessell, T.M., and Edlund, T. (2002). Progressive induction of caudal neural character by graded Wnt signaling. Nature Neuroscience, 5, 525-532.

Pun, S., Sigrist, M., Santos, A.F., Roegg, Sanes, J.R., Jessell, T.M., Arber, S., and Caroni, P. (2002). An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles. Neuron, 34, 357-370.

Livet, J., Sigrist, M., Stroebel, S., Price, S.R., Henderson, C.E., Jessell, T.M, and Arber S. (2002). ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools. Neuron. 2002 Aug 29;35(5):877-92.

Wichterle, H., Lieberam, I., Porter, J., and Jessell, T.M. (2002). Directed differentiation of embryonic stem cells into motor neurons. Cell. 2002 Aug 9;110(3):385-97.

Hippenmeyer, S., Shneider, N.A., Birchmeier, C., Burden, S.J., Jessell, T.M., and Arber, S. (2002). A role for Neuregulin 1 signaling in muscle spindle differentiation. Neuron 36, 1035-1049.

2001

Pierani, A. L. Moran-Rivard, M.J. Sunshine, D.R. Littman, M. Goulding, and T.M. Jessell (2001). Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron. 29, 367-384.

Muhr, J., Andersson, E., Persson, M., Jessell, T.M. and Ericson, J. (2001). Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube. Cell, 104, 861-873.

Briscoe, J., Chen, Y., Jessell, T.M. and Struhl, G. (2001). A hedgehog-insensitive form of patched provides evidence for direct long-range patterning activity of Sonic hedgehog in the neural tube. Molecular Cell 7, 1279-1291.

Novitch, B.G., Chen, A.I., and Jessell, T.M. (2001). Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. Neuron, 31, 773-789.

Vallstedt, A., Muhr, J., Pattyn, A., Pierani, A., Mendelsohn, M., Sander, M., Jessell, T., and Ericson, J. (2001). Different levels of repressor activity assign redundant and specific roles to Nkx6 genes during motor neuron and interneuron specification. Neuron, 31, 743-755.

Liu, J.P., Laufer, E. and Jessell, T.M. (2001). Assigning the positional identity of spinal motor neurons: rostrocaudal patterning of Hox-c protein expression by FGFs, Gdf11 and Retinoids. Neuron, 32, 997-1012.

Yang, X, Arber, S., William, C., Li, L., Tanabe, Y., Jessell, T.M., Birchmeier, C., and Burden, S.T. Patterning of Muscle Acetylcholine Receptor Gene Expression in the Absence of Motor Innervation. Neuron, 30, 399-410.

Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, Jessell TM, and Costantini F. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1:4.

Wilson, S.I., Rydstrom, A., Trimborn, T., Willert, K., Nusse, R., Jessell, T.M., Edlund, T. The status of Wnt signaling regulates neural and epidermal fates in the chick embryo. Nature, 411, 325-330.

2000

Lee, K.J., Dietrich, P. and Jessell, T.M. (2000). Genetic ablation reveals an essential role for the roof plate in dorsal interneuron specification. Nature, 403, 734-740. 

Placzek, M., Dodd, J. and Jessell, T.M. (2000). The case for floor plate induction by the notochord. Curr Opin Neurobiol 10, 15-22.

Briscoe, J., Pierani, A., Jessell, T.M. and Ericson, J. (2000). A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell. 101, 435-445.

Arber, S., Ladle, D., Lin, J., Frank, E. and Jessell, T.M. (2000). ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell, 101, 485-498.

Kania, A., Johnson, R.L. and Jessell, T.M. (2000). Coordinate roles for LIM homeobox genes in directing the dorsoventral trajectory of motor axons in the vertebrate limb. Cell. 102, 161-173.

Sander, M., Paydar, S., Ericson, J., Briscoe, J., German, M., Jessell, T.M. and Rubenstein, J. (2000). Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes and Development. 14, 2134-2139. 

Jessell, T.M. (2000) Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nature Reviews Genetics. 1, 20-29. 

Liem, K.F. Jr. Jessell, T.M. and Briscoe J. (2000). Regulation of the neural patterning activity of Sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites. Development, 127, 4855-4866.

Jessell, T.M. and Sanes, J.R. Development: The decade of the developing brain. Current Opinion in Neurobiology. 10, 599-611.

Liu, A. X., Du, W., Liu, J.P., Jessell, T.M. and Prendergast, G.C RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors. Mol. Cell. Biol. 20, 6105-6113.

Gunhaga, L., Jessell, T.M. and Edlund, T. Sonic hedgehog specifies cells characteristic of the ventral telecephalon at gastrula stages in chick embryos. Development. 127, 3283-3293.

Brown, A., Yates, P.A., Burrola, P. Ortuno, D., Vaidya, A., Jessell, T.M., Pfaff, S.L., O'Leary, D.D.M. and Lemke, G. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling. Cell. 102, 77-88.

Tsang, T.E., Shawlot, W., Kinder, S.J., Kobayashi, A., Kwan, K.M., Schughart, K., Kania, A., Jessell, T.M., Behringer, R.B., Tam, P.P. Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo. Dev. Biology 223, 77-90.

Wilson, S.I., Graziano, E., Harland, R., Jessell, T.M. and Edlund, T. An early requirement for FGF signaling in the differentiation of neural cells in the chick embryo. Current Biology. 10, 421-429.

Albright, T., Jessell, T.M., Kandel, E. and Posner, M.I. Neural science: A century of progress and the mysteries that remain. Cell 100/Neuron 25, Supplement S1-S55.

1999

Briscoe, J., Sussel, L., Serup, P., Hartigan-O'Connor, D., Jessell, T.M., Rubenstein, J.L.R. and Ericson, J. (1999). Homeobox gene Nkx2.2 and the specification of neuronal identity by graded Sonic hedgehog signaling. Nature, 398, 622-627.

Lee, K.J. and Jessell, T.M. (1999). The specification of dorsal cell fates in the vertebrate central nervous system. Ann. Rev. Neurosci. 22, 261-294.

Edlund, T. and Jessell, T.M. (1999). Progression from extrinsic to intrinsic signaling in cell fate specification: a view from the nervous system. Cell, 96, 211-224.

Pierani, A., Brenner-Morton, S., Chiang, C., and Jessell, T.M. (1999). A sonic hedgehog-independent, retinoid activated pathway of neurogenesis in the ventral spinal cord. Cell, 97, 903-915.

Arber, S., Han, B., Mendelsohn, M., Smith, M., Jessell, T.M., and Sockanathan, S. (1999). Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron, 23, 659-674.

Swindell, E.C., Thaller, C., Sockanathan, S., Petkovich, M., Jessell, T.M., and Eichele, G. (1999). Complementary regions of retinoic acid production and degradation in the early chick embryo. Developmental Biology, 216, 282-296. 

Shawlot, W., Wakamiya, M., Kwan, K.M., Kania, A., Jessell, T.M., and Behringer, R.R. Lim1 is required in both primitive streak-derived streak-derived tissues and visceral endoderm for head formation in the mouse. Development, 126, 4925-4932.

Muhr, J., Graziano, E., Wilson, S., Jessell, T.M. and Edlund, T. Convergent inductive signals specify midbrain, hindbrain and spinal cord identity in gastrula stage chick embryos. Neuron, 23, 689-702.

Alder, J., Lee, K., Jessell, T.M., and Hatten, M.B. Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells. Nature Neuroscience, 2, 535-540.

Li, Hao, Arber, S., Jessell, T.M. and Edlund H. (1999). Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hb9. Nature Genetics, 23, 67-70.

1998

Ensini, M., Tsuchida, T.N., Belting, H.G. and Jessell, T.M. (1998). Control of rostrocaudal pattern in the spinal cord: Assignment of motor neuron subtype identity is initiated by signals from paraxial mesoderm. Development, 125, 969-982.

Sockanathan, S. and Jessell, T.M. (1998). Post-mitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Cell 94, 503-514.

Lee, K.J., Mendelsohn, M. and Jessell, T.M. (1998). Neuronal patterning by BMPs: A requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord. Genes and Development, 12, 3394-3407.

Tanabe, Y., William, C. and Jessell, T.M. (1998). Specification of motor neuron identity by the MNR2 homeodomain protein. Cell, 95, 67-80.

Lin, J.H., Saito, T., Anderson, D.J., Lance-Jones, C., Jessell, T.M. and Arber, S. (1998). Functionally-related motor neuron pools and muscle sensory afferent subtypes defined by coordinate ETS gene expression. Cell, 95, 393-407.

Liu, J.P. and Jessell, T.M. (1998). A role for rhoB in the delamination of neural crest cells from the dorsal neural tube. Development, 125, 5055-5067.

Dodd, J., Jessell, T.M. and Placzek, M. (1998). When and where of floor plate induction. Science, 282, 1654-1657.

Ericson, J., Norlin, S., Jessell, T.M. and Edlund, T. Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary. Development, 125, 1005-1015.

Streit, A., Lee, K., Woo, I., Roberts, C., Jessell, T.M., and Stern, C.D. Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo. Development, 125, 507-519.

1997

Ahlgren, U., Pfaff, S.L., Jessell, T.M., Edlund, T. and Edlund, H. (1997). Independent requirement for Isl1 in the formation of pancreatic mesenchyme and islet cells. Nature, 385, 257-260.

Ericson, J., Rashbass, P., Schedl, A., Brenner-Morton, S., Kawakami, A., van Heyningen, V., Jessell, T.M., Briscoe, J. (1997). Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90, 169-180.

Liem, K., Tremml, G. and Jessell, T.M. (1997). A role for the roof plate and its resident TGFb-related proteins in neuronal patterning in the dorsal spinal cord. Cell 91, 127-138.

Ericson, J., Briscoe, J., Rashbass, P., van Heyningen, V. and Jessell, T.M. (1997). Graded Shh signaling and the specification of cell fate in the ventral neural tube. Cold Spring Harbor Symposium 62, p 451-466.

Muhr, J., Jessell, T.M. and Edlund, T. Assignment of early caudal identity to neural plate cells by a signal from caudal paraxial mesoderm. Neuron, 19, 487-502.

1996

Pfaff, S., Mendelsohn, M., Stewart, C., Edlund, T. and Jessell, T. M. (1996). Requirement for LIM homeobox gene Isl-1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Cell 84, 309-320.

Ericson, J., Morton, S., Kawakami, A., Roelink, H., Jessell, T.M. (1996). Two critical periods of sonic hedgehog signaling required for the specification of motor neuron identity. Cell 87, 661-673.

Tanabe, Y. and Jessell, T.M. (1996). Diversity and pattern in the developing spinal cord. Science 274, 1115-1123.

1995

Roelink, H., Porter, J.A., Chiang, C., Tanabe, Y., Chang, D.T., Beachy, P.A., and Jessell, T.M. (1995). Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 81, 445-455.

Ericson, J., Muhr, J., Placzek, M., Lints, T., Jessell, T.M. and Edlund, T. (1995). Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell 81, 747-756.

Tanabe, Y, Roelink, H, and Jessell, T.M. (1995). Induction of motor neurons by sonic hedgehog is independent of floor plate differentiation. Current Biology 5, 651-658.

Ruiz i Altaba, A., Roelink, H., and Jessell, T.M. (1995). Restrictions to floor plate induction by vertebrate hedgehog and winged-helix genes in the neural tube of frog embryos. Mol. Cell Neurosci. 6, 106-121.

Ruiz i Altaba, A., Placzek, M., Baldassare, M., Dodd, J., and Jessell, T.M. (1995). Early stages of notochord and floor plate development in chick embryos defined by normal and induced expression of HNF-3b. Dev. Biol. 170, 299-313.

Liem, K. F. Jr., Tremml, G., Roelink, H. R., and Jessell T. M. (1995). Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979.

Riddle, R.D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T.M. and Tabin, C. (1995). Induction of the LIM homeobox gene Lmx-1 by Wnt-7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.

Ericson, J., Muhr, J., Jessell, T.M., Edlund, T. Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube. Int. J. Dev. Biol. 39, 809-816.

1994

Roelink, H., Augsburger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruiz i Altaba, A., Tanabe, Y., Placzek, M., Edlund, T., Jessell, T.M. and Dodd, J. (1994). Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775.

Serafini, T., Kennedy, T.E., Galko, M.J., Mirzyan, M., Jessell, T.M. and Tessier-Lavigne, M. (1994). The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 78, 409-424.

Weinstein, D., Ruiz i Altaba, A., Chen, W. S., Hoodless, P., Prezioso, V. R., Jessell, T. M. and Darnell, Jr., J. E. (1994). The winged-helix transcription factor HNF-3 is required for notochord development in the mouse embryo. Cell 78, 575-588.

Tsuchida, T., Ensini, M., Morton, S., Baldassare, M., Edlund, T., Jessell, T.M., and Pfaff, S. (1994). Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 79, 957-970.

Felsenfeld, D.P., Hynes, M.A., Furley, A.J., Skolar, K.M. and Jessell, T.M. (1994). Dual functions of TAG-1: Surface TAG-1 mediates homophilic but neurite outgrowth on TAG-1 depends on both L1 and integrin function. Neuron 12, 675-690.

1993

Xu, Y., Baldassare, M., Fisher, P., Rathbun, G., Oltz, E., Yancopoulos, G.D., Jessell,T.M. and Alt, F. (1993). LH-2: A LIM/homeodomain gene expressed in developing lymphocytes and neural cells. Proc. Natl. Acad. Sci. 90, 227-231.

Placzek, M., Jessell, T.M. and Dodd, J. (1993). Induction of floor plate differentiation by contact-dependent, homeogenetic signals. Development 117, 205-218.

Jessell, T.M. and Kandel, E.R. (1993). Synaptic transmission: a bidirectional and self-modifiable form of cell-cell communication. Cell 72/Neuron 10, 1-30.

Yamada, T., Pfaff, S., Edlund, T. and Jessell, T.M. (1993). Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell 73, 673-686.

Basler, K., Edlund, T., Jessell, T.M., Yamada, T. (1993). Control of cell pattern in the neural tube: regulation of cell differentiation by dorsalin-1, a novel TGF family member Cell 73, 687-702

Ruiz i Altaba, A., Cox, C., Jessell, T.M., and Klar, A. (1993). Ectopic expression of a floor plate marker in frog embryos injected with the midline transcription factor Pintallavis. Proc. Natl. Acad. Sci. 90, 8268-8272.

Ruiz i Altaba, A., Prezioso, V., Darnell, J. and Jessell,T.M. (1993). Sequential expression of HNF-3b and HNF3a by embryonic organizing centers: the dorsal lip/node, notochord and floor plate. Mechanisms of Development 44, 91-108.

Tsiotra, P.C., Karagogeos, D., Theodorakis, K., Michaelidis, T. M., Modi, W. S., Furley, A.J., Jessell, T.M. and Papamatheakis, J. Isolation of the cDNA and chromosomal localization of the gene encoding the human axonal glycoprotein TAG-1. Genomics 18, 562-567.

Ruiz i Altaba, A., Cox, C., Jessell, T.M., and Klar, A Ectopic expression of a floor plate marker in frog embryos injected with the midline transcription factor Pintallavis. Proc. Natl. Acad. Sci. 90, 8268-8272.

1992

Jessell, T.M. and Melton, D.A. (1992). Diffusible factors in vertebrate embryonic induction. Cell 68, 257-270.

Jessell, T.M. and Dodd, J. (1992). Floor plate-derived signals and the control of neural cell pattern in vertebrates. Harvey Lecture Series 86, 87-128.

Klar,A., Baldassare, M. and Jessell, T.M. (1992). F-spondin; a gene expressed at high levels in the developing floor plate encodes a secreted protein which promotes neuronal adhesion and neurite outgrowth. Cell 69, 95-110.

Ericson, J., Thor, S., Edlund, T., Jessell, T.M. and Yamada, T. (1992). Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science 256, 1555-1560

Ruiz i Altaba, A. and Jessell, T.M. (1992). Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: Involvement in the development of the neural axis. Development 116, 81-93. 

Wagner, M., Han, B. and Jessell, T.M. (1992). Regional difference in retinoid release from neural tissue determined by an in vitro reporter assay. Development 116, 55-66.

Klar, A., Jessell, T.M. and Ruiz i Altaba, A. (1992). Control of floor plate identity and function in the embryonic nervous system. Cold Spring Harbor Symp. Quant. Biol. 54, 473-482.

1991

Yamada, T., Placzek, M., Tanaka. H, Dodd, J. and Jessell, T.M. (1991). Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord. Cell 64, 635-647.

Ruiz i Altaba, A. and Jessell, T.M. (1991). Retinoic acid modifies the pattern of cell differentiation in the central nervous system of neurula stage Xenopus embryos. Development 112, 945-958.

Placzek, M., Tessier-Lavigne, M., Yamada, T., Dodd, J. and Jessell, T.M. (1991). The guidance of developing axons by diffusible chemoattractants. Cold Spring Harbor Symposium 55, 279-289

Karagogeos, D., Morton, S.B., Casano, F., Dodd, J. and Jessell, T.M. (1991). Developmental expression of the axonal glycoprotein TAG-1: Differential regulation by central and peripheral neurons in vitro. Development 112, 51-67.

Placzek, M., Yamada, T., Tessier-Lavigne, M., Jessell, T.M. and Dodd, J. (1991). Control of dorsoventral pattern in vertebrate neural development: induction and polarizing properties of the floor plate. Development Suppl. 2, 105-122.

1990

Jessell, T.M., Hynes, M.A. and Dodd, J. (1990). Carbohydrates and carbohydrate binding proteins in the nervous systems: Expression and possible functions. Carbohydrates and carbohydrate binding proteins in the nervous systems: Expression and possible functions. Ann. Rev. Neurosci. 13, 227-255.

Julius, D., Huang, K.N., Livelli, T.J., Axel, R., and Jessell, T.M. (1990). The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors. Proc. Natl. Acad. Sci. USA 87, 928-932.

Hynes, M.A., Gitt, M., Barondes, S., Jessell, T.M. and Buck, L.B. (1990). Selective expression of an endogenous lactose-binding lectin gene in subsets of central and peripheral neurons. J. Neuroscience 10, 1004-1013.

Furley, A.J., Morton, S.B., Manalo, D., Karagogeos, D., Dodd, J. and Jessell T.M. (1990). The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth promoting activity. Cell 61, 157-170.

Wagner, M., Thaller, C., Jessell, T.M. and Eichele, G. (1990) Polarizing activity and retinoid synthesis in the floor plate of the neural tube. Nature 345, 819-822.

Placzek, M., Tessier-Lavigne, M., Jessell, T.M. and Dodd, J. (1990). Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant. Development 110, 19-30.

Yoshimura, M. and Jessell, T.M. (1990). Amino acid-mediated EPSPs at primary afferent synapses with substantia gelatinosa neurons in the rat spinal cord. J. Physiology 430, 315-335.

Placzek, M., Tessier-Lavigne, M., Yamada, T., Jessell, T.M. and Dodd, J. (1990). Mesodermal control of neural cell identity: Floor plate induction by the notochord. Science 250, 985-988.

Scaravilli, F., Jessell, T.M., Dodd, J. and Chimelli, L. Monoclonal antibodies against sensory neuron specific antigens define the extent of neuronal abnormality in the mf mutant rat. Brain 113, 677-689.

1989

Yoshimura, M. and Jessell, T.M. (1989). Primary afferent-evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro. J. Neurophysiol. 62, 96-108.

Yoshimura, M. and Jessell, T.M. (1989). Membrane rectification and the firing properties of rat substantia gelatinosa neurones J. Neurophysiol. 62, 109-119

Jessell, T.M., Bovolenta, P., Placzek, M., Tessier-Lavigne, M. and Dodd, J.. (1989). Polarity and patterning in the neural tube: The origin and role of the floor plate. CIBA Foundation Symposium 144, 255-280.

Hynes, M.A., Buck, L.B., Gitt, M., Barondes, S., Dodd, J. and Jessell, T.M. (1989). Carbohydrate recognition in neuronal development: Structure and expression of surface oligosaccharides and b-galactoside-binding lectins. CIBA Foundation Symposium 145, 189-219.

Julius, D., Livelli, T.J., Jessell, T.M. and Axel, R. (1989). The serotonin 1c receptor is an oncogene in fibroblasts. Science 244, 1057-1062.

Molineaux, S.M., Jessell, T.M., Axel, R. and Julius, D. (1989). The 5HT 1c receptor is a prominent serotonin receptor subtype in the central nervous system. Proc. Natl. Acad. Sci. USA 86, 6793-6797.

Alvarez, F.J., Rodrigo, J., Jessell, T.M., Dodd, J. and Priestley, J.V. (1989). Morphology and distribution of primary afferent fibres expressing alpha-galactose extended oligosaccharides in the spinal cord and brainstem of the rat. Light microscopy. J. Neurocytol. 18, 611-629.

Alvarez, F.J., Rodrigo, J., Jessell, T.M., Dodd, J. and Priestley, J.V. Ultrastructure of primary afferent fibres and terminals expressing alpha-galactose extended oligosaccharides in the spinal cord and brainstem of the rat. J. Neurocytol. 18, 631-645.

Chou, D.K.H., Dodd, J., Jessell, T.M., Costello, C. and Jungalwala, F.B. Identification of ASIALO-GM1 (a-fucose)-b-galactose glycolipid expressed by subsets of rat dorsal root ganglion neurons. J. Biol. Chem. 264, 3409-3415.

Hynes, M.A., Dodd, J. and Jessell, T.M. (1989). "Carbohydrate recognition, cell interactions and vertebrate neural development" In: Neurobiology of Glycoconjugates. New York, Plenum Publishing Corporation. 337-365.

1988

Jessell, T.M. (1988). Adhesion molecules and the hierarchy of neural development. Neuron 1, 3-13.

Dodd, J., Morton, S.B., Karagogeos, D., Yamamoto, M. and Jessell, T.M. (1988). Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1, 105-116.

Rutishauser, U. and Jessell, T.M. (1988). Cell adhesion molecules in vertebrate neural development. Physiol. Rev. 68, 819-857.

Womack, M.D., MacDermott, A.B. and Jessell, T.M. (1988). Sensory transmitters regulate intracellular calcium concentration in dorsal horn neurons. Nature 334, 351-353.

Julius, D., MacDermott, A.B., Axel, R., and Jessell T.M. (1988). Molecular characterization of a functional cDNA encoding the serotonin 1c receptor. Science 241, 558-564.

Dodd, J. and Jessell, T.M. (1988). Axon guidance and the patterning of neuronal projections in vertebrates. Science 242, 692-699.

Tessier-Lavigne, M., Placzek, M., Lumsden, AG.S., Dodd, J. and Jessell, T.M. (1988). Chemotropic guidance of developing axons in the mammalian central nervous system. Nature 336, 775-778.

Julius, D., MacDermott, A., Jessell, T.M., Huang, K., Molineaux, S., Schieren, I. and Axel, R. Functional expression of the 5HT1c receptor in neuronal and non-neuronal cells. Cold Spring Harbor Symp 53, 385-393.

1986

Jessell, T.M., Yoshioka, K., and Jahr, C.E. Amino acid receptor-mediated transmission at primary afferent synapses in rat spinal cord. J. Exp. Biol. 124, 239-258.

Regan, L.J., Dodd, J., Barondes, S.H. and Jessell, T.M. ). Selective expression of endogenous lactose-binding lectins and lactoseries glycoconjugates in subsets of rat sensory neurons. Proc. Natl. Acad. Sci. USA 83, 2248-2252.

Dodd, J. and Jessell, T.M. Cell surface glycoconjugates and carbohydrate-binding proteins: possible recognition signals in sensory neuron development. J. Exp. Biol. 124, 225-238.

Jessell, T.M. and Dodd, J. Neurotransmitters and differentiation antigens in subsets of sensory neurons projecting to the spinal dorsal horn Neuropeptides in Neurologic and Psychiatric Disease, eds JB Martin and J Barchas New York, Raven Press pp 111-133.

1985

Womack, M.D., Hanley, M.R. and Jessell, T.M. Functional substance P receptors on a rat pancreatic acinar cell line. J. Neurosci. 5, 3370-3378.

Dodd, J. and Jessell, T.M. Lactoseries carbohydrates specify subsets of dorsal root ganglion neurons projecting to the superficial dorsal horn of rat spinal cord. J. Neurosci. 5, 3278-3294.

Jessell ,T.M. and Dodd, J. (1985). Structure and expression of differentiation antigens on functional subclasses of primary sensory neurons. Philosoph. Transact. Royal Soc. B. 308, 271-281.

1984

Dodd, J., Solter, D. and Jessell, T.M. Monoclonal antibodies against carbohydrate differentiation antigens identify subsets of primary sensory neurons. Nature 311, 469-472.

1983

Barnstable, C., Jessell, T.M., Sanes, J., Stevens, C. and Robertson M. How molecular is neurobiology? Nature 306,14-16.

Snary, D., Flint, J.E., Wood, J.N., Scott, M.T., Chapman, M.D., Dodd, J., Jessell, T.M. and Miles, M.A. A monoclonal antibody with specificity for Trypanosoma cruzi, central and peripheral neurons and glia. Clin. Exp. Immunol. 54, 617-624

Jahr, C.E. and Jessell, T.M. ATP Excites a subpopulation of rat dorsal horn neurons. Nature 304, 730-733.

Dodd, J., Jahr, C.E., Hamilton, P.N., Heath, M.J.S., Matthew, W.D. and Jessell, T.M. Cytochemical and physiological properties of sensory and dorsal horn neurons that transmit cutaneous sensation. Cold Spring Harbor Symp. Quant. Biol. 48, 685-695.

1982

Jessell, T.M. Fifty years of substance P. Nature 295,551-553.

Jessell, T.M. Substance P in nociceptive sensory neurons. Ciba Foundation Symposium 91, 225-248.

Jessell, T.M Neurotransmitters in pain pathways. Lancet II, 1084-1088.

Wood, J.N., Hudson, L., Jessell, T.M. and Yamamoto, M. A monoclonal antibody defining shared antigenic determinants on sub-populations of mammalian neurons and Trypanosoma cruzi parasites. Nature 296, 34-38.

Forda, S.R., Jessell, T.M, Kelley, J.S. and Rand, R.P. (1982). Use of the patch electrode for sensitive high resolution extracellular recording. Brain Research 249, 371-378

1981

Yamamoto, M., Steinbusch, H.W.M. and Jessell, T.M. Differentiated properties of identified serotonin neurons in dissociated cultures of embryonic rat brain stem. J. Cell Biol. 91, 142-152.

Jessell, T.M. (1981). The role of substance P in sensory transmission and pain perception. Advances in Psychopharmacology 28, 189-198.

1980

Suzue, T. and Jessell, T.M. Opiate analgesics and endorphins inhibit rat dorsal root potential in vitro. Neuroscience Letters 16, 161-166.

Jessell, T.M. and Kelly, J.S. Peptide pathology: of mice and men. Nature 285, 131-132.

Yaksh, T.L., Jessell, T.M., Gamse, R., Mudge, A.W. and Leeman, S.E. Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature 286: 155-157.

Jessell, T.M. and Yamamoto, M. (1980). Development of spinal sensory systems. Nature 288, 640-641.

1979

Fischbach, G.D., Frank, E., Jessell, T.M., Rubin, L.L. and Schuetze, S.M. Accumulation of acetylcholine receptors and acetylcholinesterase at newly formed nerve-muscle synapses. Pharmacological Reviews 30, 411-428.

Jessell, T.M., Siegel, R.E. and Fischbach, G.D. Induction of acetylcholine receptors on cultured skeletal muscle by a factor extracted from brain and spinal cord. Proc. Natl. Acad. Sci. USA 76, 5397-5401.

Yaksh, T.L., Farb, D.H., Leeman, S.E. and Jessell, T.M. Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science 206, 481-483.

Theriault, E., Otsuka, M. and Jessell, T.M. Capsaicin-evoked release of substance P from primary sensory neurons. Brain Research 170, 209-213.

Jessell, T.M., Tsunoo, A., Kanazawa, I. and Otsuka, M Substance P: Depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons. Brain Research 168, 247-259.

1978

Jessell, T.M., Cuello, A.C. and Iversen, L.L. Capsaicin induced depletion of substance P from primary sensory neurons. Brain Research 152, 183-188.

Reubi, J.C., Emson, P.C., Jessell, T.M. and Iversen, L.L. Effects of GABA dopamine and substance P on the release of newly synthesized 3H-5-hydroxytryptamine from rat substantia nigrain vitro. Naunyn Shmeideberg Arch. Pharmacol. 304, 271-275

Reubi, J.C., Jessell Distribution of substance P in the pigeon brain. J. Neurochem. 31, 359-361.

Emson, P.C., Fahrenkrug, J., Shaffalitzky de Muckadell, O.B., Jessell, T.M. and Iversen, L.L. Vasoactive intestinal peptide (VIP) vesicular localization and potassium evoked release from rat hypothalamus. Brain Research 143, 174-178.

Jessell, T.M., Emson, P.C., Paxinos, G. and Cuello, A.C. Topographical projections of substance P and GABA pathways in the striato and pallido-nigral system: a biochemical and immunohistochemical study. Brain Research 152, 487-498.

Cuello, A.C., Emson, P.C., Paxinos, G. and Jessell, T.M Substance P containing and cholinergic projections from the habenula. Brain Research 149, 413-429.

Emson, P.C., Jessell, T.M., Paxinos, G. and Cuello, A.C. Substance P in the amygdaloid complex, bed nucleus and stria terminalis of the rat brain. Brain Research 149, 97-105.

Reubi, J.C., Iversen, L.L. and Jessell, T.M. Regulation of GABA release by dopamine in the rat substantia nigra In: Advances in Biochemical Psychopharmacology, Vol 19 eds. PG Roberts, G Woodruff and LL Iversen New York, Raven Press. 401-404.

Weitsch-Dick, F., Jessell, T.M. and Kelly, J.S. The selective neuronal uptake and release of 3H-DL-2-4-diaminobutyric acid by rat cerebral cortex. J. Neurochem. 30, 799-806.

Jessell, T.M. (1978). Substance P release from the rat substantia nigra. Brain Research 151, 469-478.

1977

Emson, P.C., Cuello, A.C., Paxinos, G., Jessell, T.M. and Iversen, L.L. The origin of substance P and acetylcholine projections to the ventral segmental area and interpeduncular nucleus in the rat. Acta. Physiol. Scand. Suppl. 452, 43-46.

Gauchy, C.M., Iversen, L.L. and Jessell, T.M. The spontaneous and evoked release of newly-synthesized 14C-GABA from rat cerebral cortex in vitro. Brain Research 138, 374-379

Reubi, J.C., Iversen, L.L. and Jessell, T.M. Dopamine selectively increases 3H-GABA release from slices of rat substantia nigra in vitro. Nature 268, 652-654.

Jessell, T.M. and Iversen, L.L. Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature: 268, 549-551.

Cuello, A.C., Jessell, T.M., Kanazawa, I. and Iversen, L.L. Substance P: localization in synaptic vesicles in rat central nervous system. J. Neurochem. 29, 747-751.

Emson, P., Kanazawa, I., Cuello, A.C. and Jessell, T.M. Substance P pathways in rat brain. Biochem Soc Transactions 5, 187-189.

Phillipson, O.T., Emson, P.C., Horn, A.S. and Jessell, T.M. (1977). Evidence concerning the anatomical location of the dopamine-stimulated adenylate cyclase in the substantia nigra. Brain Research 136, 45-58.

1976

Kanazawa, I. and Jessell, T.M. Post-mortem changes and regional distribution of substance P in the rat and mouse nervous system. Brain Research 117, 362-367.

Jessell, T.M., Iversen, L.L. and Kanazawa, I. Release and metabolism of substance P in rat hypothalamus. Nature 264, 81-83.

Geffen, L.B., Jessell, T.M., Cuello, A.C. and Iversen L.L. Release of dopamine from dendrites in rat substantia nigra. Nature 260, 258-260.